Litcius/Paper detail

An Activity-Guided Map of Electrophile-Cysteine Interactions in Primary Human T Cells

Ekaterina V. Vinogradova, Xiaoyu Zhang, David Remillard, Daniel C. Lazar, Radu M. Suciu, Yujia Wang, Giulia Bianco, Yu Yamashita, Vincent M. Crowley, Michael A. Schafroth, Minoru Yokoyama, David B. Konrad, Kenneth M. Lum, Gabriel M. Simon, Esther K. Kemper, Michael R. Lazear, Sifei Yin, Megan M. Blewett, Melissa M. Dix, Nhan Nguyen, Maxim N. Shokhirev, Emily N. Chin, Luke L. Lairson, Bruno Melillo, Stuart L. Schreiber, Stefano Forli, John R. Teijaro, Benjamin F. Cravatt

2020Cell372 citationsDOIOpen Access PDF

Topics & Concepts

ElectrophileCysteineBiologyImmune systemSmall moleculeProteomeBiochemistryCell biologyEnzymeImmunologyCatalysisClick Chemistry and ApplicationsPeptidase Inhibition and AnalysisAdenosine and Purinergic Signaling