An Activity-Guided Map of Electrophile-Cysteine Interactions in Primary Human T Cells
Ekaterina V. Vinogradova, Xiaoyu Zhang, David Remillard, Daniel C. Lazar, Radu M. Suciu, Yujia Wang, Giulia Bianco, Yu Yamashita, Vincent M. Crowley, Michael A. Schafroth, Minoru Yokoyama, David B. Konrad, Kenneth M. Lum, Gabriel M. Simon, Esther K. Kemper, Michael R. Lazear, Sifei Yin, Megan M. Blewett, Melissa M. Dix, Nhan Nguyen, Maxim N. Shokhirev, Emily N. Chin, Luke L. Lairson, Bruno Melillo, Stuart L. Schreiber, Stefano Forli, John R. Teijaro, Benjamin F. Cravatt
Topics & Concepts
ElectrophileCysteineBiologyImmune systemSmall moleculeProteomeBiochemistryCell biologyEnzymeImmunologyCatalysisClick Chemistry and ApplicationsPeptidase Inhibition and AnalysisAdenosine and Purinergic Signaling