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An evaluation of existing QSAR models and structural alerts and development of new ensemble models for genotoxicity using a newly compiled experimental dataset

Prachi Pradeep, Richard Judson, David M. DeMarini, Nagalakshmi Keshava, Todd M. Martin, Jeffry L. Dean, Catherine F. Gibbons, Anita Simha, Sarah H. Warren, Maureen R. Gwinn, Grace Patlewicz

2021Computational Toxicology34 citationsDOIOpen Access PDF

Topics & Concepts

Quantitative structure–activity relationshipIn silicoGenotoxicityComputational biologyAmes testRanking (information retrieval)Computer scienceBiologyMachine learningGeneticsGeneChemistrySalmonellaOrganic chemistryToxicityBacteriaCarcinogens and Genotoxicity AssessmentComputational Drug Discovery MethodsAnimal testing and alternatives
An evaluation of existing QSAR models and structural alerts and development of new ensemble models for genotoxicity using a newly compiled experimental dataset | Litcius