Development of sterically hindered SPOs and enantioselective Ni−Al bimetallic catalyzed C−H cyclization of 4-oxoquinazolines with tethered alkenes
Yaqi Zhang, Qiang Ni, Bendu Pan, Long Jiang, Liqin Qiu
Topics & Concepts
Steric effectsEnantioselective synthesisBimetallic stripCatalysisChemistryYield (engineering)PhosphineIntramolecular forceRegioselectivityOrganic chemistryCombinatorial chemistryMedicinal chemistryMaterials scienceMetallurgyCatalytic C–H Functionalization MethodsQuinazolinone synthesis and applicationsSynthetic Organic Chemistry Methods