Genome-Wide Characterization of Zebrafish Endogenous Retroviruses Reveals Unexpected Diversity in Genetic Organizations and Functional Potentials
Jun Bai, Zuozhen Yang, Hao Li, Yun Hong, Dongdong Fan, Aifu Lin, Li‐xin Xiang, Jian-zhong Shao
Abstract
genes, and expression profiles in embryos and tissues. The result helps uncover the evolutionarily conserved and fish-specific ERVs, as well as the immune-relevant ERVs in response to virus infection. This study demonstrates the previously unrecognized abundance, diversification, and extensive activity of ERVs at the early stage of ERV evolution.
Topics & Concepts
Endogenous retrovirusBiologyGenomeZebrafishGeneticsGeneDanioPhylogeneticsEvolutionary biologyChromosomal and Genetic VariationsCRISPR and Genetic EngineeringGenomics and Phylogenetic Studies