Repression of p53 function by SIRT5-mediated desuccinylation at Lysine 120 in response to DNA damage
Xing Liu, Fangjing Rong, Jinhua Tang, Chunchun Zhu, Xiaoyun Chen, Shuke Jia, Zixuan Wang, Xueyi Sun, Hongyan Deng, Huangyuan Zha, Gang Ouyang, Wuhan Xiao
Topics & Concepts
DNA damagePsychological repressionCell biologyApoptosisSuccinylationDNA repairLysineSuppressorFunction (biology)ChemistryBiologyGeneDNAAcetylationGene expressionBiochemistryAmino acidSirtuins and Resveratrol in MedicineCancer-related Molecular PathwaysAutophagy in Disease and Therapy