The PIEZO1/miR-155-5p/GDF6/SMAD2/3 signaling axis is involved in inducing the occurrence and progression of osteoarthritis under excessive mechanical stress.
Chaoren Qin, Feng Yan, Zhaowei Yin, Changjiang Wang, Rui Yin, Yang Li, Kai Chen, Tianqi Tao, Kaibin Zhang, Yiqiu Jiang, Jianchao Gui
Topics & Concepts
ChondrocyteOsteoarthritisIn vivoWestern blotCell biologyAggrecanCartilageEx vivoBiologyChemistryMedicinePathologyArticular cartilageAnatomyBiochemistryGeneBiotechnologyAlternative medicineOsteoarthritis Treatment and MechanismsMicroRNA in disease regulationConnective Tissue Growth Factor Research