Selective VEGFR-2 inhibitors: Synthesis of pyridine derivatives, cytotoxicity and apoptosis induction profiling
Amal AbdelHaleem, Amira O. Mansour, Marwa AbdelKader, Reem K. Arafa
Topics & Concepts
ChemistryDownregulation and upregulationDU145Cell cycleCancer cellApoptosisKinaseCyclin-dependent kinaseCytotoxic T cellCell cycle checkpointCaspase 3AngiogenesisCancer researchCell biologyBiochemistryIn vitroProgrammed cell deathBiologyCancerLNCaPGeneticsGeneAngiogenesis and VEGF in CancerSynthesis and biological activityHER2/EGFR in Cancer Research