Transcriptomic profiling revealed the role of apigenin-4′-O-α-L-rhamnoside in inhibiting the activation of rheumatoid arthritis fibroblast-like synoviocytes via MAPK signaling pathway
Dan Cao, Qiqi Fan, Zhiqi Li, Meilin Chen, Yangyu Jiang, Ruichao Lin, Li J, Chongjun Zhao
Topics & Concepts
ApigeninMAPK/ERK pathwayRANKLChemistryp38 mitogen-activated protein kinasesSignal transductionFibroblastPharmacologyCancer researchActivator (genetics)ReceptorMedicineIn vitroBiochemistryFlavonoidAntioxidantRheumatoid Arthritis Research and TherapiesFlavonoids in Medical ResearchNatural Compounds in Disease Treatment