Deoxygenative 1,3-carbophosphination of allylic alcohols enabled by manganese pincer catalyst
Xin Chen, Guanbo Li, Hui Ma, Sheng‐Yin Zhao, Weiping Liu
Abstract
The first manganese-catalyzed three-component coupling between secondary alcohol, allylic alcohol, and phosphine via borrowing hydrogen is described. This four-stage, one-pot reaction afforded ε-hydroxy phosphines in a step-economical fashion.
Topics & Concepts
ChemistryAllylic rearrangementPincer movementManganeseCatalysisOrganic chemistryCombinatorial chemistryAsymmetric Hydrogenation and CatalysisChemical Synthesis and ReactionsOrganophosphorus compounds synthesis