miR-140 inhibits osteosarcoma progression by impairing USP22-mediated LSD1 stabilization and promoting p21 expression
Wei Liu, Dunwei Wang, Lidi Liu, Lin Wang, Ming Yan
Abstract
. This study revealed a role for miR-140 in the restriction of osteosarcoma development and identified miR-140 as a potential target for therapeutic intervention.
Topics & Concepts
OsteosarcomaCancer researchExpression (computer science)ChemistryCell biologyBiologyComputer scienceProgramming languageMicroRNA in disease regulationCancer-related molecular mechanisms researchCircular RNAs in diseases