Catalyst-free synthesis of diverse fluorescent polyoxadiazoles for the facile formation and morphology visualization of microporous films and cell imaging
Junyao Xie, Niu Niu, Xinyao Fu, Xiang Su, Dong Wang, Anjun Qin, Ting Han, Ben Zhong Tang
Abstract
generate oxadiazole moieties in polymer backbones. The obtained PODs possess good solubility, high thermal and morphological stability, and excellent film-forming ability. The introduction of aggregation-induced emission (AIE) moieties together with the inherent structural features of PODs endow these polymers with multiple functionalities. The AIE-active linear PODs can form fluorescent microporous films with stable and ordered structures based on the simple breath figure patterning method, and the self-assembly morphologies can be directly visualized by fluorescence microscopy in a high-contrast and sensitive manner. Moreover, both the linear and hyperbranched AIE-active PODs possess excellent biocompatibility, good lysosome specificity, and excellent photobleaching resistance, which enable them to serve as promising lysosome-specific fluorescent probes in biological imaging.