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Scaling analysis reveals the mechanism and rates of prion replication in vivo

Georg Meisl, Timothy D. Kurt, Itzel Condado Morales, Cyrus Bett, Silvia Sorce, Mario Nuvolone, Thomas C. T. Michaels, Daniel Heinzer, Merve Avar, Samuel I. A. Cohen, Simone Hornemann, Adriano Aguzzi, Christopher M. Dobson, Christina J. Sigurdson, Tuomas P. J. Knowles

2021Nature Structural & Molecular Biology36 citationsDOIOpen Access PDF

Topics & Concepts

In vivoProtein aggregationIn vitroPrion proteinBiologyCell biologyBiophysicsFragmentation (computing)Amyloid (mycology)Replication (statistics)ChemistryKineticsVirologyDiseaseBiochemistryGeneticsMedicinePathologyEcologyPhysicsQuantum mechanicsBotanyPrion Diseases and Protein MisfoldingAlzheimer's disease research and treatmentsTrace Elements in Health
Scaling analysis reveals the mechanism and rates of prion replication in vivo | Litcius