Review of Coronavirus Disease (COVID-19)
A Ademu, Abubakar Abubakar, H Lu, C Stratton, Y Tang, C Huang, Y Wang, Z Li, L Ren, J Zhao, Y Hu, L Zhang, G Fan, J Xu, X Gu, S Perlman, J Netland, R Lu, X Zhao, J Li, P Niu, B Yang, H Wu, W Wang, H Song, B Huang, N Zhu, Y Yin, R Wunderink, Mers, T Phan, L Hsu, P Chia, J Lim, M Lipsitch, D Swerdlow, L Finelli, M Lipsitch, C Donnelly, C Fraser, I Blake, A Cori, I Dorigatti, N Ferguson, T Garske, H Mills, S Riley, J Lei, Y Kusov, R Hilgenfeld, M Letko, A Marzi, V Munster, C Pyle, F Uwadiae, D Swieboda, J Harker, C Chen, X Zhang, Z Ju, W He, F Bennardo, C Buffone, A Giudice, S Rose-John, T Lupia, S Scabini, S Pinna, G Di Perri, F De Rosa, S Corcione, Y Yang, F Peng, R Wang, K Guan, T Jiang, G Xu, J Sun, C Chang, T Ai, Z Yang, H Hou, C Zhan, C Chen, W Lv, Q Tao, Z Sun, L Xia, Y Li, L Xia, H Bai, B Hsieh, Z Xiong, K Halsey, J Choi, T Tran, I Pan, L Shi, D Wang, J Mei
Abstract
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a novel virus that causes severe acute respiratory syndrome, spread globally from Wuhan, China, at the end of 2019. The SARS-Cov-2 virus was declared a global pandemic by the World Health Organization in March 2020. This is an analysis of current literature on the epidemiology, pathophysiology, diagnosis, management, and future outlook of Corona Virus Disease 2019 (COVID-19). For related articles, several databases were searched. While it will only be possible to determine the full health, social and economic effects of this global catastrophe when the pandemic ends, this analysis reflects a picture of the current state of the pandemic. Therapeutic management options include the use of glucocorticoids, remdesivir, chloroquine and hydroxychloroquine plus azithromycin, mectizan, vitamin C+D and calcium and others. Some preventive strategies for COVID-19 are: use of face mask, covering of coughs and sneezes, observation of physical and social distance, refraining from touching the eyes, nose and mouth and seeking medical attention early in case there are symptoms suggestive of the infection. This review article focusses on pathophysiology, clinical manifestations, diagnosis, management, and preventive measures for covid-19