Juvenile and adult vulvar pemphigoid, an under recognized entity: Case series of fourteen patients
Hanan Rashid, J Oldhoff, Martha D. Esajas, Gilles F.H. Diercks, Hendri H. Pas, Maria C. Bolling, Barbara Horváth
Abstract
Vulvar pemphigoid (VP) is a rare subtype of mucous membrane pemphigoid (MMP), which is a heterogeneous group of autoimmune subepidermal blistering diseases with predominantly mucosal involvement and characterized by autoantibodies against structural proteins in the epidermal basement membrane zone (EBMZ).1 In MMP, various mucosal sites can be simultaneously or separately affected. Mucosal lesions tend to heal with scar formation and may result in loss of function of the affected area.
Topics & Concepts
MedicineBasement membraneDermatologyMucous membraneBullous pemphigoidPemphigoidAutoantibodyPathologyImmunologyAntibodyAutoimmune Bullous Skin DiseasesCoagulation, Bradykinin, Polyphosphates, and AngioedemaUrticaria and Related Conditions