Mitochondrial dynamics and metabolic attributes regulate function of natural killer cell and infiltration in tumor microenvironment modulating disease progression
Sayak Ghosh, R. K. Dutta, Devyani Goswami, Debapriya Ghatak, Rudranil De
Topics & Concepts
Tumor microenvironmentImmune systemCell biologyBiologyCancer researchMitochondrionGlutaminolysisCarcinogenesisPI3K/AKT/mTOR pathwayCytotoxic T cellCancer cellReprogrammingNatural killer cellTumor progressionMechanistic target of rapamycinProgrammed cell deathCellMetabolic pathwayCell metabolismGlutamineImmunotherapyAutophagyCancer immunotherapyMitochondrial ROSInflammationImmunologyT cellmTORC1ChemistryCytokineFunction (biology)Nitric oxideHypoxia (environmental)Immune Cell Function and InteractionT-cell and B-cell ImmunologyEndoplasmic Reticulum Stress and Disease