Matrine inhibits synovial angiogenesis in collagen-induced arthritis rats by regulating HIF-VEGF-Ang and inhibiting the PI3K/Akt signaling pathway
Limei Ao, Han Gao, Lifen Jia, Shimin Liu, Jie Guo, Bingzhen Liu, Qiumei Dong
Topics & Concepts
AngiogenesisVascular endothelial growth factorProtein kinase BPI3K/AKT/mTOR pathwayCancer researchHuman umbilical vein endothelial cellUmbilical veinNeovascularizationMedicineImmunologyChemistrySignal transductionInternal medicineEndocrinologyIn vitroBiochemistryVEGF receptorsRheumatoid Arthritis Research and TherapiesNatural Compounds in Disease TreatmentSignaling Pathways in Disease