The Antibacterial Activity of Kaempferol Combined with Colistin against Colistin-Resistant Gram-Negative Bacteria
Huijing Zhou, Mengxin Xu, Wenhui Guo, Zhuocheng Yao, Xin Du, Lijiang Chen, Yao Sun, Yishi Shi, Jianming Cao, Tieli Zhou
Abstract
. The synergistic effect of combined application may be attributed to membrane permeability. Due to the low cytotoxicity of the combined concentration, the combination exhibits a promising future for use in clinical anti-infection treatments. This finding might broaden the potential applications for COL.
Topics & Concepts
ColistinGram-negative bacteriaAntibioticsGramMicrobiologyBacteriaBiologyGram-negative bacterial infectionsMCR-1MedicineEnterobacteriaceaeGeneticsEscherichia coliGeneAntibiotic Resistance in BacteriaPhenothiazines and Benzothiazines Synthesis and ActivitiesPharmacological Effects of Natural Compounds