Effects of a cancer-associated mutation and multiple serine phosphorylation on poly(ADP-ribose) polymerase 2
Bridget T. Hughes, Shubham Chatterjee, Mozhdeh Ghafari, G. Andrés Cisneros
Topics & Concepts
SerineMutantMutationPhosphorylationPoly ADP ribose polymeraseChemistryDNA damageMolecular biologyBiologyDNA repairWild typePolymeraseDNABiochemistryCell biologyGenePARP inhibition in cancer therapy