Ent-eudesmane sesquiterpenoids with anti-neuroinflammatory activity from the marine-derived fungus Eutypella sp. F0219
Zhongping Jiang, Rui Su, Mengting Chen, Junyi Li, Hanyu Chen, Lu Yang, Fei‐Fei Liu, Jin Liu, Congjun Xu, Wan‐Shan Li, Yong Rao, Ling Huang
Topics & Concepts
NeuroinflammationStereochemistryMicrogliaDownregulation and upregulationTwo-dimensional nuclear magnetic resonance spectroscopyChemistryRegulatorInflammationTumor necrosis factor alphaProinflammatory cytokineFungusStructure–activity relationshipBiochemistryBiologyGeneImmunologyBotanyIn vitroMicrobial Natural Products and BiosynthesisMarine Sponges and Natural ProductsNatural product bioactivities and synthesis