Current systematic reviews and meta-analyses of COVID-19
Mahmoud Nassar, Nso Nso, Mostafa Alfishawy, Anastasia Novikov, Salim Yaghi, Luis Medina, Bahtiyar Toz, Sofia Lakhdar, Zarwa Idrees, Yungmin Kim, Dawa Gurung, Raheel S Siddiqui, David Zheng, Mariam Agladze, Vikram Sumbly, J. K. Sandhu, Francisco Cuevas Castillo, Nadya Chowdhury, Ravali Kondaveeti, Sakil Bhuiyan, Laura Guzman Perez, R. Ranat, Carlos Gonzalez, Harangad S. Bhangoo, John R. Williams, Alaa Eldin Osman, Joyce Kong, Jonathan Ariyaratnam, Mahmoud Mohamed, Ismail Omran, M. G. Herrera López, Akwe Nyabera, Ian Landry, Saba Iqbal, Anoosh Zafar Gondal, Sameen Hassan, Ahmed Daoud, Bahaaeldin Baraka, Theo Trandafirescu, Vincent Rizzo
Abstract
BACKGROUND: Coronavirus disease 2019 (COVID-19) has left a significant impact on the world's health, economic and political systems; as of November 20, 2020, more than 57 million people have been infected worldwide, with over 1.3 million deaths. While the global spotlight is currently focused on combating this pandemic through means ranging from finding a treatment among existing therapeutic agents to inventing a vaccine that can aid in halting the further loss of life. AIM: To collect all systematic reviews and meta-analyses published related to COVID-19 to better identify available evidence, highlight gaps in knowledge, and elucidate further meta-analyses and umbrella reviews that are yet to be performed. METHODS: We explored studies based on systematic reviews and meta-analyses with the key-terms, including severe acute respiratory syndrome (SARS), SARS virus, coronavirus disease, COVID-19, and SARS coronavirus-2. The included studies were extracted from Embase, Medline, and Cochrane databases. The publication timeframe of included studies ranged between January 01, 2020, to October 30, 2020. Studies that were published in languages other than English were not considered for this systematic review. The finalized full-text articles are freely accessible in the public domain. RESULTS: smoking, cancer, and transplant. CONCLUSION: Among the included articles, it is clear that further research is needed regarding treatment options and vaccines. With more studies, data will be less heterogeneous, and statistical analysis can be better applied to provide more robust clinical evidence. This study was not designed to give recommendations regarding the management of COVID-19.