Taurine-Conjugated Mussel-Inspired Iron Oxide Nanoparticles with an Elongated Shape for Effective Delivery of Doxorubicin into the Tumor Cells
Nimisha Singh, Nadine Millot, Lionel Maurizi, Gérard Lizard, Rajender Kumar
Abstract
-tetrazolium) and Annexin V-FITC assays used to evaluate cell toxicity and apoptosis reveal a dose-dependent nature of nanorods and can overcome the side effects of using free DOX with a targeted action.
Topics & Concepts
DoxorubicinBiocompatibilityDrug deliveryConjugated systemNanoparticleTaurineChemistryCancer cellCytotoxicityBiophysicsTargeted drug deliveryNanotechnologyMaterials scienceBiochemistryIn vitroCancerAmino acidChemotherapyOrganic chemistrySurgeryInternal medicineBiologyPolymerMedicinePolymer Surface Interaction StudiesLayered Double Hydroxides Synthesis and ApplicationsPolymer-Based Agricultural Enhancements