Emodin alleviated pulmonary inflammation in rats with LPS-induced acute lung injury through inhibiting the mTOR/HIF-1α/VEGF signaling pathway
Xiaoqian Li, Cong Shan, Zhonghua Wu, Hongji Yu, Aidong Yang, Bo Tan
Topics & Concepts
PI3K/AKT/mTOR pathwayBronchoalveolar lavageInflammationVascular endothelial growth factorMedicineLipopolysaccharideEmodinTumor necrosis factor alphaSignal transductionImmunologyLungChemistryCancer researchInternal medicineBiochemistryChromatographyVEGF receptorsPhytochemistry and biological activity of medicinal plantsEicosanoids and Hypertension PharmacologyBiological and pharmacological studies of plants