Allosteric Regulation of BH3 Proteins in Bcl-xL Complexes Enables Switch-like Activation of Bax
Christian Bogner, Justin Kale, Justin Pogmore, Xiaoke Chi, Aisha Shamas‐Din, Cécile Fradin, Brian Leber, David W. Andrews
Topics & Concepts
Bcl-xLAllosteric regulationBiologyActivator (genetics)Cell biologyApoptosisFunction (biology)Plasma protein bindingProgrammed cell deathBiochemistryEnzymeReceptorCell death mechanisms and regulationRNA Interference and Gene DeliveryNeuroscience and Neuropharmacology Research