Identification of a lncRNA/circRNA-miRNA-mRNA network in Nasopharyngeal Carcinoma by deep sequencing and bioinformatics analysis
Shilei Liu, Xiaoxiao Li, Qingming Xie, Sai Zhang, Xujun Liang, Shisheng Li, Pengfei Zhang
Abstract
The regulatory network revealed in this study may help comprehensively elucidate the ceRNA mechanisms driving NPC, and provide novel candidate biomarkers for evaluating the prognosis of NPC.
Topics & Concepts
Competing endogenous RNAmicroRNABiologyKEGGComputational biologyNasopharyngeal carcinomaGeneNon-coding RNAGene regulatory networkRegulation of gene expressionBioinformaticsGene expressionLong non-coding RNAGeneticsRNAGene ontologyMedicineInternal medicineRadiation therapyCancer-related molecular mechanisms researchCircular RNAs in diseasesMicroRNA in disease regulation