Molecular mechanisms of hepatoprotective effect of tectorigenin against ANIT-induced cholestatic liver injury: Role of FXR and Nrf2 pathways
Peng Cao, Jun Gan, Sanlan Wu, Yixin Hu, Bin Xia, Xiaoyue Li, Hongan Zeng, Bingyu Cheng, Huifan Yu, Fei Li, Luqin Si, Jiangeng Huang
Topics & Concepts
Farnesoid X receptorTauroursodeoxycholic acidBile acidCholestasisLiver injuryBile Salt Export PumpGCLCChemistryUrsodeoxycholic acidMultidrug resistance-associated protein 2Glycocholic acidPharmacologyInternal medicineTaurocholic acidBiochemistryEndocrinologyCholic acidBiologyGlutathioneMedicineNuclear receptorATP-binding cassette transporterUnfolded protein responseEnzymeEndoplasmic reticulumTranscription factorTransporterGeneDrug Transport and Resistance MechanismsDrug-Induced Hepatotoxicity and ProtectionGenomics, phytochemicals, and oxidative stress