The Association between Coagulation and Atrial Fibrillation
Saira Rafaqat, Sanja Gluščević, Dimitrios Patoulias, Saima Sharif, Aleksandra Klisić
Abstract
The existing literature highlights the presence of numerous coagulation factors and markers. Elevated levels of coagulation factors are associated with both existing and newly diagnosed cases of atrial fibrillation (AF). However, this article summarizes the role of coagulation in the pathogenesis of AF, which includes fibrinogen and fibrin, prothrombin, thrombomodulin, soluble urokinase plasminogen activator receptor, von Willebrand factor, P-selectin, D-dimer, plasminogen activator inhibitor-1, and platelet activation. Coagulation irregularities play a significant role in the pathogenesis of AF.
Topics & Concepts
ThrombomodulinCoagulationFibrinogenPathogenesisAtrial fibrillationMedicinePlasminogen activatorFibrinVon Willebrand factorInternal medicineFibrinolysisImmunologyThrombinPlateletAtrial Fibrillation Management and OutcomesVenous Thromboembolism Diagnosis and ManagementAcute Myocardial Infarction Research