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Defunctionalisation catalysed by boron Lewis acids

Huaquan Fang, Martin Oestreich

2020Chemical Science77 citationsDOIOpen Access PDF

Abstract

coordination, and this Lewis adduct is a key intermediate that enables various reduction processes. This system can be tuned by variation of the electronic and structural properties of the borane catalyst, and together with different hydride sources high chemoselectivity can be achieved. This Perspective provides a comprehensive summary of various defunctionalisation reactions such as deoxygenation, decarbonylation, desulfurisation, deamination, and dehalogenation, all of which catalysed by boron Lewis acids.

Topics & Concepts

Lewis acids and basesHeteroatomBoronCleavage (geology)HydrideChemistryCatalysisCarbon fibersBond cleavagePolymer chemistryOrganic chemistryMaterials scienceRing (chemistry)HydrogenFracture (geology)Composite numberComposite materialOrganoboron and organosilicon chemistryAsymmetric Hydrogenation and CatalysisAsymmetric Synthesis and Catalysis