CuAAC ensembled 1,2,3-triazole linked nanogels for targeted drug delivery: a review
Gurleen Singh, Ather Majeed, Riddima Singh, Nancy George, Gurjaspreet Singh, Sofia Gupta, Harminder Singh, Gurpreet Kaur, Jandeep Singh
Abstract
CuAAC 'click' methodology, as scaffolds for targeted drug delivery and their assimilation into nanomedicine. In addition, it elaborates the ability of CuAAC to graft specific moieties and conjugating biomolecules like proteins and growth factors, onto orthogonally functionalized polymer chains with various chemical groups resulting in nanogels that are not only more appealing but also more effective at delivering drugs, thereby enhancing their site-specific target approach and initiating selective therapies.
Topics & Concepts
ChemistryDrug deliveryCombinatorial chemistryDrugTriazoleTargeted drug deliveryNanotechnologyPharmacologyMedicineMaterials scienceOrganic chemistryGraphene and Nanomaterials ApplicationsNanoparticle-Based Drug DeliveryNanomaterials for catalytic reactions