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Case Report: COVID-19 with Bilateral Adrenal Hemorrhage

Jorge Álvarez Troncoso, M Larrauri, María Dolores Montero Vega, Rebeca Gil Vallano, Esmeralda Palmier Peláez, Patricia Martín Rojas‐Marcos, Fátima Martín-Luengo, Paula Lázaro del Campo, Carmen Rosario Herrero Gil, Elena Trigo Esteban

2020American Journal of Tropical Medicine and Hygiene46 citationsDOIOpen Access PDF

Abstract

A 70-year-old Dominican Republic man presented with lower back pain for 10 days. Fifteen days before pain onset, he had low-grade fever, chills, and asthenia, and 4 days before admission, he had constipation, malaise, generalized weakness, anorexia, nausea, and vomiting. On admission, the patient was afebrile and hypotensive, with a heart rate of 105 and an oxyhemoglobin saturation on room air of 95%. Hyponatremia, lymphopenia, elevated C-reactive protein, and ferritin were observed in complementary tests. Computed tomography (CT) scan showed findings consistent with COVID-19 bilateral bronchopneumonia, and an increase in size and blurring (loss of the Y shape) of both adrenals indicative of acute bilateral adrenal hemorrhage. The patient tested negative by reverse transcription polymerase chain reaction (RT-PCR) of nasopharyngeal swab, yet positive for IgG and IgM by ELISA, suggesting COVID-19 diagnosis.

Topics & Concepts

HyponatremiaMedicineChillsVomitingAnorexiaNauseaMalaiseAbdominal painGastroenterologyConstipationInternal medicineTachypneaAnesthesiaTachycardiaAdrenal Hormones and DisordersNeuroblastoma Research and TreatmentsThermal Regulation in Medicine