Thermoresponsive shear-thinning hydrogel (T-STH) hemostats for minimally invasive treatment of external hemorrhages
Marvin Mecwan, Reihaneh Haghniaz, Alireza Hassani Najafabadi, Kalpana Mandal, Vadim Jucaud, Johnson V. John, Ali Khademhosseini
Abstract
rat liver bleeding model. Furthermore, once the hemorrhage is stabilized, our T-STH can be easily removed using a cold saline wash without any rebleeding or leaving any residues. Taken together, our T-STH can be used as a first aid hemostat to treat external hemorrhages in emergency situations.
Topics & Concepts
HemostatSelf-healing hydrogelsHypertonic salineIn vivoWhole bloodEx vivoBiomedical engineeringHemostaticsHemostatic AgentSurgerySalineCoagulationClotting timeMedicineChemistryHemostasisAnesthesiaPolymer chemistryBiologyPsychiatryBiotechnologyHemostasis and retained surgical itemsTrauma, Hemostasis, Coagulopathy, ResuscitationSurgical Sutures and Adhesives