Induction of COX-2 by feline calicivirus via activation of the MEK1-ERK1/2 pathway, and attenuation of feline lung inflammation and injury by MEK1 inhibitor AZD6244 (selumetinib)
Ying Liu, Wenda Shi, Qianqian Xie, Jigui Wang, Chenchen Gu, Zhi-hui Ji, Jun Xiao, Weiquan Liu
Topics & Concepts
Feline calicivirusSelumetinibCATSIn vivoInflammationLungIn vitroCancer researchBiologyMedicineKinaseMAPK/ERK pathwayChemistryImmunologyCell biologyMEK inhibitorInternal medicineBiochemistryBiotechnologyViral gastroenteritis research and epidemiologyAnimal Virus Infections StudiesVeterinary medicine and infectious diseases