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Histone lactylation-driven YTHDF2 promotes non-small cell lung cancer cell glycolysis and stemness by recognizing m6A modification of SFRP2

Shu Zhao, Jing Cheng, Gang Zhou, Longyun Tao, Jiaojiao Xing, Lulu Liu, Zhenhong Chen, Peng Song

2025Biochemical Pharmacology11 citationsDOI

Topics & Concepts

BiologyGene knockdownChromatin immunoprecipitationHistoneCancer researchCell biologyMolecular biologyGene expressionCell cultureBiochemistryPromoterGeneGeneticsRNA modifications and cancerCancer-related gene regulationEpigenetics and DNA Methylation
Histone lactylation-driven YTHDF2 promotes non-small cell lung cancer cell glycolysis and stemness by recognizing m6A modification of SFRP2 | Litcius