Unravelling the anticancer potency of 1,2,4-triazole-N-arylamide hybrids through inhibition of STAT3: synthesis and in silico mechanistic studies
Abdallah Turky, Ashraf H. Bayoumi, Farag F. Sherbiny, Khaled El‐Adl, Hamada S. Abulkhair
Topics & Concepts
CytotoxicityIn silicoChemistryIn vitroPotencyMechanism of actionDocking (animal)TriazoleIC50StereochemistryPharmacologyCombinatorial chemistryBiochemistryBiologyMedicineGeneOrganic chemistryNursingClick Chemistry and ApplicationsSynthesis and biological activityQuinazolinone synthesis and applications