Higher anhedonia during withdrawal from initial opioid exposure is protective against subsequent opioid self-administration in rats
Yayi Swain, Peter Muelken, Annika Skansberg, Danielle Lanzdorf, Zachary Haave, Mark LeSage, Jonathan C. Gewirtz, Andrew C. Harris
Topics & Concepts
AnhedoniaSelf-administrationOpioidKindlingMedicinePsychologyDrug withdrawalPharmacologyAnesthesiaPsychiatryDrugInternal medicineReceptorSchizophrenia (object-oriented programming)EpilepsyNeurotransmitter Receptor Influence on BehaviorStress Responses and CortisolMemory and Neural Mechanisms