Micheliolide ameliorates lipopolysaccharide-induced acute kidney injury through suppression of NLRP3 activation by promoting mitophagy via Nrf2/PINK1/Parkin axis
Xianghong Lei, Jiyang Wang, Fengxia Zhang, Xianhu Tang, Fengxia He, Shengyu Cheng, Fangqin Zou, Wenjun Yan
Topics & Concepts
ParkinMitophagyPINK1LipopolysaccharideMedicineAutophagyPharmacologyChemistryCell biologyBiologyImmunologyInternal medicineParkinson's diseaseApoptosisBiochemistryDiseaseAcute Kidney Injury ResearchInflammasome and immune disordersDialysis and Renal Disease Management