Clinical Course and Outcome of Human Monkeypox in Nigeria
Dimie Ogoina, Michael Iroezindu, Hendris Izibewule James, Regina Oladokun, Adesola Yinka-Ogunleye, Paul Wakama, Bolaji Otike-Odibi, Liman Muhammed Usman, Emmanuel Obazee, Olusola Aruna, Chikwe Ihekweazu
Abstract
In a retrospective review of hospital records of 40 human monkeypox cases from Nigeria, the majority developed fever and self-limiting vesiculopustular skin eruptions. Five deaths were reported. Compared to human immunodeficiency virus (HIV)-negative cases, HIV type 1-coinfected cases had more prolonged illness, larger lesions, and higher rates of both secondary bacterial skin infections and genital ulcers.
Topics & Concepts
MonkeypoxMedicineRetrospective cohort studyLimitingSex organViral diseaseHuman immunodeficiency virus (HIV)Medical recordPediatricsDermatologyImmunologySurgeryGeneticsBiochemistryGeneBiologyVacciniaEngineeringRecombinant DNAMechanical engineeringChemistryPoxvirus research and outbreaksHerpesvirus Infections and TreatmentsPlant Virus Research Studies