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Perfluorooctane sulfonate induces suppression of testosterone biosynthesis via Sertoli cell-derived exosomal/miR-9-3p downregulating StAR expression in Leydig cells

Jiyan Huang, Hang Ren, Anni Chen, Ting Li, Hongxia Wang, Lianlian Jiang, Shaokai Zheng, Qi Han, Binyan Ji, Xipei Wang, Jianhua Qu, Jianya Zhao, Lianglin Qiu

2022Environmental Pollution28 citationsDOI

Topics & Concepts

Sertoli cellLeydig cellTestosterone (patch)Internal medicineEndocrinologyPerfluorooctaneSteroidogenic acute regulatory proteinSpermSecretionBiologyIn vitroChemistryAndrologySpermatogenesisHormoneGene expressionGeneMedicineSulfonateBiochemistryLuteinizing hormoneSodiumOrganic chemistryReproductive System and PregnancySperm and Testicular FunctionReproductive Biology and Fertility
Perfluorooctane sulfonate induces suppression of testosterone biosynthesis via Sertoli cell-derived exosomal/miR-9-3p downregulating StAR expression in Leydig cells | Litcius