The natural medicinal fungus Huaier promotes the anti-hepatoma efficacy of sorafenib through the mammalian target of rapamycin-mediated autophagic cell death
Zhengguang Zhang, Cunsi Shen, Fuqiong Zhou
Topics & Concepts
SorafenibPI3K/AKT/mTOR pathwayAutophagyApoptosisHepatocellular carcinomaLiver cancerCancer researchMedicinePharmacologyGrowth inhibitionCell growthAnnexinFlow cytometryBiologyImmunologyBiochemistryGeneticsCancer Mechanisms and TherapyAutophagy in Disease and TherapyUbiquitin and proteasome pathways