Litcius/Paper detail

GCN2 kinase activation by ATP-competitive kinase inhibitors

Colin P. Tang, Owen Clark, John R. Ferrarone, Carl Campos, Alshad S. Lalani, John D. Chodera, Andrew M. Intlekofer, Olivier Elemento, Ingo K. Mellinghoff

2021Nature Chemical Biology57 citationsDOIOpen Access PDF

Topics & Concepts

NeratinibKinaseErbBCancer researchCell biologymTORC1BiologyChemistrySignal transductionCancerGeneticsPI3K/AKT/mTOR pathwayTrastuzumabBreast cancerProtein Degradation and InhibitorsMelanoma and MAPK PathwaysPI3K/AKT/mTOR signaling in cancer