The E3 ubiquitin ligase TRIM31 plays a critical role in hypertensive nephropathy by promoting proteasomal degradation of MAP3K7 in the TGF-β1 signaling pathway
Jie Zhang, Lei Cao, Xiaohong Wang, Qian Li, Meng Zhang, Cheng Cheng, Liwen Yu, Fei Xue, Wenhai Sui, Shangwen Sun, Na Li, Peili Bu, Bingyu Liu, Fei Gao, Junhui Zhen, Guohai Su, Cheng Zhang, Chengjiang Gao, Meng Zhang, Yun Zhang
Topics & Concepts
Ubiquitin ligaseUbiquitinSignal transductionAngiotensin IIProtein kinase AKinaseMAPK/ERK pathwayFibrosisInflammationChemistryCell biologyMedicineCancer researchInternal medicineBiologyBiochemistryReceptorGeneFerroptosis and cancer prognosisImmune cells in cancerChronic Kidney Disease and Diabetes