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ISSAAC-seq enables sensitive and flexible multimodal profiling of chromatin accessibility and gene expression in single cells

Wei Xu, Weilong Yang, Yunlong Zhang, Ya‐Wen Chen, Ni Hong, Qian Zhang, Xuefei Wang, Yukun Hu, Kun Song, Wenfei Jin, Xi Chen

2022Nature Methods109 citationsDOI

Topics & Concepts

ChromatinBiologyChIA-PETGene expressionComputational biologyCell typeGene expression profilingGeneCellCell biologyGeneticsChromatin remodelingSingle-cell and spatial transcriptomicsGenomics and Chromatin DynamicsEpigenetics and DNA Methylation
ISSAAC-seq enables sensitive and flexible multimodal profiling of chromatin accessibility and gene expression in single cells | Litcius