Litcius/Paper detail

Inhibition of the BTK-IDO-mTOR axis promotes differentiation of monocyte-lineage dendritic cells and enhances anti-tumor T cell immunity

Madhav Sharma, Rafał Pacholczyk, Huidong Shi, Zuzana Berrong, Yousef Zakharia, Austin Greco, Chang-Sheng S. Chang, Sudharshan Eathiraj, Eugene P. Kennedy, Thomas F. Cash, Roni J. Bollag, Ravindra Kolhe, Ramses Sadek, Tracy L. McGaha, Paulo C. Rodrı́guez, Jay K. Mandula, Bruce R. Blazar, Theodore S. Johnson, David H. Munn

2021Immunity76 citationsDOIOpen Access PDF

Topics & Concepts

BiologyLineage (genetic)ImmunityMonocyteBruton's tyrosine kinasePI3K/AKT/mTOR pathwayImmunologyCancer researchCell biologyCell lineageCellular differentiationImmune systemGeneticsSignal transductionGeneTyrosine kinaseImmune Cell Function and InteractionImmunotherapy and Immune ResponsesCancer Immunotherapy and Biomarkers