Design and synthesis of pyrazolone-based compounds as potent blockers of SARS-CoV-2 viral entry into the host cells
Vincent A. Obakachi, Narva Deshwar Kushwaha, Babita Kushwaha, Mavela Cleopus Mahlalela, Suraj Shinde, Idowu Kehinde, Rajshekhar Karpoormath
Topics & Concepts
ChemistryGlycoproteinViral envelopeViral entryCoronavirusViral structural proteinVirologyCytoplasmBiochemistryVirusCoronavirus disease 2019 (COVID-19)Viral replicationBiologyInfectious disease (medical specialty)PathologyDiseaseMedicineSARS-CoV-2 and COVID-19 ResearchComputational Drug Discovery Methodsinterferon and immune responses