Association of physical activity with chronic kidney disease: a systematic review and dose-response meta-analysis
Yongjian Zhu, Yongjun Bu, Guofu Zhang, Shibin Ding, Desheng Zhai, Zhongxiao Wan, Zengli Yu
Abstract
BACKGROUND: The relationship between physical activity (PA) and chronic kidney disease (CKD) risk was inconsistent. We therefore conducted a systematic review and dose-response meta-analysis to comprehensively evaluate the association of PA and CKD. RESULTS: = 0.135). The risk of CKD was reduced by 2% (OR = 0.98, 95% CI = 0.96-1.00) with each 10 metabolic equivalent h/week increment of PA. CONCLUSIONS: The findings demonstrated that the higher level of PA might have a protective effect against the risk of CKD. METHODS: Electronic databases PubMed and Embase were searched up to March 11, 2020. Observational studies investigated the relationship between PA and CKD risk with estimated effects (relative risk, hazard ratio, or OR) with 95 % CI among adults were included.