390P Vepdegestrant, a proteolysis targeting chimera (PROTAC) estrogen receptor (ER) degrader, in ER+/human epidermal growth factor receptor 2 (HER2)- advanced breast cancer: Update of dose escalation results from a phase I/II trial
Erika Hamilton, Hyo S. Han, Anne F. Schott, Antoinette R. Tan, Rita Nanda, Dejan Juric, N. Hunter, Pamela N. Münster, Bruno Fang, G. Zahrah, J. Ranciato, Richard Gedrich, Eric Zhi, Y. Zhang, Weiwei Tan, C. Mather, Jessica M. Perkins, Sibyl Anderson, Sara A. Hurvitz
Topics & Concepts
MedicineInternal medicineBreast cancerTolerabilityFulvestrantOncologyMetastatic breast cancerAdverse effectCancerPhases of clinical researchGastroenterologyEstrogen receptorChemotherapyAdvanced Breast Cancer TherapiesProtein Degradation and InhibitorsHER2/EGFR in Cancer Research