Prevalence of Aminoglycoside Resistance Genes and Molecular Characterization of a Novel Gene, <i>aac(3)-IIg</i> , among Clinical Isolates of the Enterobacter cloacae Complex from a Chinese Teaching Hospital
Xinyi Zhu, Peizhen Li, Changrui Qian, Hongmao Liu, Hailong Lin, Xueya Zhang, Qiaoling Li, Junwan Lu, Xi Lin, Teng Xu, Hailin Zhang, Yunliang Hu, Qiyu Bao, Kewei Li
Abstract
Members of the Enterobacter cloacae complex are important opportunistic human pathogens capable of causing a wide variety of infections. During recent decades, aminoglycoside-resistant E. cloacae complex isolates have increasingly been reported and have become a major concern. Here, we employed high-throughput sequencing in combination with specific PCR assays to investigate the prevalence of aminoglycoside resistance genes among 170 isolates of the E. cloacae complex collected from a teaching hospital in Wenzhou, China.
Topics & Concepts
Enterobacter cloacaeAminoglycosideBiologyGeneEnterobacteriaceae InfectionsEnterobacterMicrobiologyAntibioticsGeneticsEnterobacteriaceaeEscherichia coliAntibiotic Resistance in BacteriaEnterobacteriaceae and Cronobacter ResearchSalmonella and Campylobacter epidemiology