PD-L1 interacts with Frizzled 6 to activate β-catenin and form a positive feedback loop to promote cancer stem cell expansion
Lingchen Fu, Jia Fan, Sudipa Maity, Grant McFadden, Yixin Shi, Wei Kong
Topics & Concepts
BiologyFrizzledCancer stem cellCancer researchWnt signaling pathwayCancerTumor progressionLGR5MetastasisCateninCell biologySignal transductionStem cellGeneticsCancer Cells and MetastasisCancer Immunotherapy and BiomarkersImmunotherapy and Immune Responses