Selective Electrochemical Oxidation of Functionalized Pyrrolidines
Nicholas R. Deprez, Dane J. Clausen, Jia‐Xuan Yan, Feng Peng, Shaoguang Zhang, Jongrock Kong, Yanguang Bai
Abstract
A method for the selective electrochemical aminoxyl-mediated Shono-type oxidation of pyrrolidines to pyrrolidinones is described. These transformations show the high selectivity and functional group compatibility. This chemistry also demonstrates the use of an operationally simple ElectraSyn 2.0 and cost-effective stainless-steel electrode for the electrochemical oxidation of functionalized pyrrolidines.
Topics & Concepts
ChemistryElectrochemistryCombinatorial chemistryCompatibility (geochemistry)SelectivityPyrrolidinonesElectrodeFunctional groupOrganic chemistryPolymerChemical engineeringCatalysisPhysical chemistryEngineeringOxidative Organic Chemistry ReactionsRadical Photochemical ReactionsAdvanced Synthetic Organic Chemistry