Cutaneous adverse effects of biologic medications
Selena R. Pasadyn, Daniel Knabel, Anthony P. Fernandez, Christine Warren
Abstract
Biologic therapies have become widely used but often cause cutaneous adverse effects. The authors discuss the cutaneous adverse effects of tumor necrosis factor (TNF) alpha inhibitors, epidermal growth factor receptor (EGFR) inhibitors, small-molecule tyrosine kinase inhibitors (TKIs), and cell surface-targeted monoclonal antibodies, including how to manage these reactions and when to refer to a dermatologist.
Topics & Concepts
MedicineAdverse effectMonoclonal antibodyEpidermal growth factor receptorTyrosine kinaseTumor necrosis factor alphaMonoclonalPharmacologyDermatologyReceptorImmunologyInternal medicineAntibodyChronic Lymphocytic Leukemia ResearchCutaneous lymphoproliferative disorders researchChemotherapy-related skin toxicity