Redox cycling of copper by coumarin-di(2-picolyl)amine hybrid molecule leads to ROS-mediated modulation of redox scavengers, DNA damage and cell death in diethylnitrosamine induced hepatocellular carcinoma
Saman Khan, Atif Zafar, Imrana Naseem
Topics & Concepts
ChemistryLigand (biochemistry)Reactive oxygen speciesApoptosisDNA damageCancer cellHepatocellular carcinomaCancer researchBiochemistryCancerReceptorDNAInternal medicineBiologyMedicineMetal complexes synthesis and propertiesComputational Drug Discovery MethodsDrug Transport and Resistance Mechanisms